Smo-Agonist

【别名】 Smo-Agonist

【CAS号】 912545-86-9

【纯度】 98%

【分子式】 C28H28ClN3OS

【分子量】 490.06

【简介】 SAG is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM); antagonizes Cyclopamine action at the Smo receptor. SAG potently activates the Hedgehog signaling pathway in Shh-light 2 cells (EC50 ~ 3 nM). Induces pathway activation independently of Ptch proteins.